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The Fine Motor Dexterity Under Dual Task in Parkinson's Disease

Conditions
Fine Motor Skill Dysfunction
Parkinson Disease
Interventions
Diagnostic Test: Fine motor dexterity test, nine hole peg test
Registration Number
NCT03589872
Lead Sponsor
T.C. ORDU ÜNİVERSİTESİ
Brief Summary

This study was planned to investigate the contribution of dual task interference on dexterity related ADL disability in patients with Parkinson's disease. We hypothesised that the dual task interference is an indicator of dexterity related ADL difficulties.

Detailed Description

We planned this study as a cross sectional trial. 53 patients with Parkinson's disease will be evaluated under 2 different task by nine hole peg test. Besides this assessment the cardinal symptoms (bradykinesia, tremor, rigidity) will be evaluated to determine their contribution on the ADL performance.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
53
Inclusion Criteria
  • Diagnosis of idiopathic Parkinson's disease according to the criteria of the United Kingdom brain Bank by neurologist
  • Age 50-90 range
  • having sufficient cognitive status according to the Mini Mental Status Evaluation (24 or above from the Mini Mental Test)
Exclusion Criteria
  • Having orthopedic and neurological disorders affecting hand function,
  • Having sensory problems,
  • Having Diabetus mellitus

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Study GroupFine motor dexterity test, nine hole peg testpatients with parkinson disease
Primary Outcome Measures
NameTimeMethod
Nine hole peg test5 minutes

The Nine-Hole Peg Test is used to measure finger dexterity in patients with various neurological diagnoses. The patient must pick up the pegs from the holes and replace them back as fast as possible. The Nine Hole Peg Test should be conducted with the dominant arm first, then nondominant hand. The time will be recorded in second to complete the test. The test will be performed under three task;

1. single task: Only nine-hole peg test

2. adding a cognitive task: Nine-hole peg test will be performed with a concurrent cognitive task. The cognitive task is a serial 7 subtraction from numbers changed between 290 and 310 during the performing nine-hole peg test. The time will be recorded.

ADL-related dexterity Questionnaire 24 (DextQ-24)10 minutes

Dexterity-related ADL difficulties were measured by the ADL-related dexterity Questionnaire 24 (DextQ-24), including 24 question dealing with bimanual and unimanual activities, which is a reliable and valid disease specific questionnaire to evaluate dexterity in patients with PD. Each question is scored between 1 (no problems) and 4 (need aid to perform task) by the patient's experience. Total score ranged from 24 points to 96 points.

Secondary Outcome Measures
NameTimeMethod
Unified Parkinson's Disease Rating Scale (UPDRS) - Section of Activities of Daily Living (ADL)10 minutes

The UPDRS- ADL section evaluates the impact of Parkinson disease on ADL according to patient's perspective. The ADL section consists of 13 items for gathering information on the patient's own perception of functional impairment due to PD. Each item scores between 0-4. 0 means normal and 4 means severe impairment. The total score change between 0-52. High scores indicate severe impairment.

Unified Parkinson's Disease Rating Scale (UPDRS) - Motor Section10 minutes

Motor section of UPDRS determines the impairment due to the Parkinson's disease. Rigidity, bradykinesia and tremor items which are relating with upper extremity function will be assessed. Each item scores between 0-4. 0 means normal and 4 means severe impairment. The total scores of rigidity, bradykinesia, and tremor, respectively range between 0-8, 0-24 and 0-16.

Modified Hoehn and Yahr Scale2 minutes

Disease progression will be assessed with modified Hoehn and Yahr Scale. The original scale included stages 1 through 5. Since then, stage 0 has been added, and stages 1.5 and 2.5 have been proposed. This modified scale allocates stages from 0 to 5 to indicate the relative level of disability.

Stage 0: No signs of disease.

Stage 1: Unilateral symptoms only.

Stage 1.5: Unilateral and axial involvement.

Stage 2: Bilateral symptoms. No impairment of balance.

Stage 2.5: Mild bilateral disease with recovery on pull test.

Stage 3: Balance impairment. Mild to moderate disease. Physically independent.

Stage 4: Severe disability, but still able to walk or stand unassisted.

Stage 5: Needing a wheelchair or bedridden unless assisted.

Trial Locations

Locations (1)

Sevim ACARÖZ CANDAN

🇹🇷

Ordu, Altinordu, Turkey

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