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Clinical Trials/NCT06270342
NCT06270342
Completed
Not Applicable

The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients

Kutahya Health Sciences University1 site in 1 country60 target enrollmentJune 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
Kutahya Health Sciences University
Enrollment
60
Locations
1
Primary Endpoint
The Minnesota Manual Dexterity Test
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls. Additionally, another aim of our study was to compare the cognitive status, quality of life, fatigue and emotional states of individuals with MS and healthy controls.

Detailed Description

The study was carried out at Kutahya Health Sciences University Evliya Çelebi Training and Research Hospital. 30 individuals with MS and 30 healthy controls, aged 18-65, were included in the study. In the evaluation, demographic and clinical data were recorded first. The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks.

Registry
clinicaltrials.gov
Start Date
June 1, 2023
End Date
December 15, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Kutahya Health Sciences University
Responsible Party
Principal Investigator
Principal Investigator

Eda Ozge OKUR

Asst. Prof.

Kutahya Health Sciences University

Eligibility Criteria

Inclusion Criteria

  • Having been diagnosed with Multiple Sclerosis for at least 1 year
  • Being between the ages of 18-65
  • Being at least a primary school graduate
  • Volunteering to participate in the study
  • EDSS score between 1 and 6.5

Exclusion Criteria

  • Patients whose Multiple Sclerosis diagnosis is uncertain
  • Having additional neurological disease that may affect clinical evaluation
  • Having a neurological and/or psychiatric disease that may affect cognitive tests
  • Having had an attack in the last 3 months

Outcomes

Primary Outcomes

The Minnesota Manual Dexterity Test

Time Frame: 30 minutes

Upper Extremity Function Evaluation. The Minnesota Manual Dexterity Test basically consists of two subtests, the placement and translation test. Completing the test faster indicates better dexterity.

Dual Task Questionnaire

Time Frame: 10 minutes

Dual Task Difficulty Evaluation. The survey consists of 10 items and is scored out of 5 points per question. A higher total score indicates worse dual task performance.

Edinburgh Handedness Questionnaire

Time Frame: 10 minutes

Hand Preference Evaluation. The total scoring is between 100 and -100, individuals with more than 40 points are given right hand; Individuals in this score range from 40 to -40 inclusive are recorded as those who use both hands actively, and individuals with scores of -40 points and below are recorded as left-handed.

Expanded Disability Status Scale

Time Frame: 10 minutes

Disability Status Evaluation. A score of 0 on the scale indicates normal neurological status, while a score of 10 means MS-related death.

Brief International Cognitive Assessment Battery for Multiple Sclerosis

Time Frame: 15 minutes

Cognitive Status Evaluation. BICAMS comprises three tests, the Symbol Digit Modalities Test (SDMT), the learning trials of the California Verbal Learning Test II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R).

Beck Depression Scale

Time Frame: 10 minutes

Emotional Status Evaluation. The lowest score that can be obtained from the scale is 0 and the highest score is 63. According to the resulting total score; It results in absence-mild, mild-moderate, moderate-severe or severe.

Fatigue Impact Scale

Time Frame: 5 minutes

Fatigue Status Evaluation. Each question receives a score between 0 (no problem) and 4 (maximum problem). The highest score is 160, and higher scores indicate fatigue.

Multiple Sclerosis Quality of Life Questionnaire-54

Time Frame: 15 minutes

Quality of Life Status Evaluation. The survey contains 54 questions consisting of 12 sections. Added 18 questions are about; general quality of life (2 items), health stress (4 items), sexual functions and satisfaction (5 items), cognitive functions (4 items), energy (1 item), pain (1 item) and social functions (1 item).

Study Sites (1)

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