Evaluating Effect of Low-Sodium and Regular Diets on Heart Failure Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Length of hospital stay
研究概览
简要总结
The purpose of this study is to understand if low sodium (cardiac) diet is indeed necessary for better health outcomes in patients who suffered heart failure. This study will investigate the association between sodium intake and risk for 30-day re-admission in Heart Failure (HF) patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Above 18 years of age
- •Hospitalization due to Heart Failure admitted within 24 hours
排除标准
- •Concomitant hypertension (blood pressure >150/90 mmHg on admission)
- •End stage renal disease (on hemodialysis or peritoneal dialysis
- •Cardiogenic shock
研究组 & 干预措施
Normal Salt Diet
3-4 gm/day salt diet
干预措施: Normal Salt Diet (Other)
Cardiac Diet
2 gm/day salt diet
干预措施: Cardiac Diet (Other)
结局指标
主要结局
Length of hospital stay
时间窗: Hospital admission to time of discharge assessed up to 1 year
number of days the patient remains hospitalized
30-day readmission
时间窗: 30 days after discharge from hospital after index event
readmission to hospital within 30 days of discharge from the index event
NT-proBNP on discharge
时间窗: time of hospital admission to 30 days after discharge
Measurement of blood levels of NT-ProBNP a biomarker for diagnosing and assessing the severity of heart failure.
Loop diuretic requirement during index admission
时间窗: time of hospital admission to 30 days after discharge
Furosemide, torsemide, and bumetanide are specific loop diuretics used in the treatment of fluid overload / retention conditions like congestive heart failure.
次要结局
未报告次要终点
研究者
Maya Guglin, MD
Section Chief, Heart Failure/Transplant/MCS at Rutgers Robert Wood Johnson Medical School
Rutgers, The State University of New Jersey