Comparing Liquid Versus Solid Forms of Sugars and Whey Protein

Not Applicable

Completed

• Conditions: Diabetes; Obesity

• Registration Number: NCT01348685
• Lead Sponsor: University of Toronto

Brief Summary

To compare the effect of eating solid vs. drinking liquid forms of gelatin, sucrose and its component mixtures and whey protein on subjective appetite and food intake in young men.

Detailed Description

Three randomized cross-over design experiments were used to compare the effect of solid and liquid forms of gelatin (6 g) in experiment 1, sucrose (75 g) and a mixture of 50% glucose/ 50% fructose (G50:F50) in experiment 2, and acid and sweet whey protein (50 g) in experiment 3 on healthy normal weight males . The controls were water (experiment 1 and 3) and calorie-free sweetened water with gelatin (sweet gelatin, experiment 1) or without gelatin (sweet control, experiment 2). Subjective average appetite was measured by visual analogue scales frequently over 1 h and ad libitum food intake was measured 1 h after the treatment consumptions.

Study Timeline

• Study Start: 2007-01
• Primary Completion: 2009-03
• Study Completion: 2009-03
• Status Verified: 2011-02
• Study First Submitted: 2011-05-04
• Study First Submitted QC: 2011-05-04
• Last Update Submitted: 2011-05-04
• Study First Posted: 2011-05-05
• Last Update Posted: 2011-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 43

Inclusion Criteria

• Healthy lean males with BMI between 18- 24.9 kg/m2 and an age range of 19 to 28 years were recruited for the three experiments.

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Exclusion Criteria

• Diabetics (fasting blood glucose ≥ 7.0 mmol/L), smokers, breakfast skippers or dieters were excluded from the experiments. Individuals under medications or with a history of liver or kidney disease and major medical or surgical event within the last six months were excluded.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
subjective appetite and short term food intake	60 min

Trial Locations

Locations (1)

University of Toronto, Department of Nutritional Sciences; 🇨🇦 Toronto, Ontario, Canada