Is Video-assisted Thoracoscopic Lobectomy a Clinical Alternative for Surgically Resectable Pathologic N2 NSCLC Patients
- Conditions
- Non-small Cell Lung Cancer
- Registration Number
- NCT03613467
- Lead Sponsor
- Tang-Du Hospital
- Brief Summary
The study was designed to compare the safety and effectiveness of vedio-assisted thoracoscopic lobectomy with open lobectomy for patients with surgically resectable pathologic N2 non-small cell lung cancer
- Detailed Description
The is a multi-center retrospective study. Patients with pathologic N2 NSCLC who underwent VATS or open lobectomy between 2014 and 2017 were included into this study. Clinical data on patient demographic, clinical characteristics, treatment and clinical outcomes will be collected to evaluate the safety and effectiveness of video-assisted thoracoscopic lobectomy for pathologic N2 NSCLC.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2145
- Patients with age > 18 years old;
- Patients with pathologically diagnosed non-small cell lung cancer;
- Patients underwent lobectomy by either VATS or thoracotomy between 2014 and 2017;
- Patients who received lymphadenectomy for all accessible lymph nodes;
- Patients with N2 lymph nodes (+) after surgeries;
- Patients with second primary tumors or multiple primary tumors;
- Patients who received chest surgeries before hospitalization;
- Patients with superior pulmonary sulcus tumor
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival 2014-2018 Overall survival
- Secondary Outcome Measures
Name Time Method Postoperative 30 and 90 days [Perioperative outcomes] 2014-2017 Postoperative 30 and 90 days \[Perioperative outcomes\]
Drainage time [Perioperative outcomes] 2014-2017 Drainage time \[Perioperative outcomes\]
Duration of hospital stay [Perioperative outcomes] 2014-2017 Duration of hospital stay \[Perioperative outcomes\]
Postoperative complications [Perioperative outcomes] 2014-2017 Postoperative complications \[Perioperative outcomes\]
Intraoperative blood loss [Perioperative outcomes] 2014-2017 Intraoperative blood loss \[Perioperative outcomes\]
Related Research Topics
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Trial Locations
- Locations (10)
China-Japan Friendship Hospital
🇨🇳Beijing, Beijing, China
China PLA General Hospital
🇨🇳Beijing, Beijing, China
Henan Cancer Hospital
🇨🇳Zhengzhou, Henan, China
Tongji Hospital Affiliated to Huazhong Technology Hospital
🇨🇳Wuhan, Hubei, China
Jiangsu cancer hospital
🇨🇳Nanjing, Jiangsu, China
Xi'an Tangdu Hospital
🇨🇳Xi'an, Shaanxi, China
Shanghai Chest Hospital
🇨🇳Shanghai, Shanghai, China
Huaxi Hospital Affiliated to Sichuan University
🇨🇳Chengdu, Sichuan, China
Tianjin Chest Hospital
🇨🇳Tianjin, Tianjin, China
First Hospital Affiliated to Zhejiang University
🇨🇳Hangzhou, Zhejiang, China
China-Japan Friendship Hospital🇨🇳Beijing, Beijing, China