NCT02108730已完成不适用
Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism
University Medicine Greifswald1 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2011年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- necessity of medication after restrictive surgery in congenital hyperinsulinism
研究概览
简要总结
Observational study in patients with non-focal congenital hyperinsulinism showing that restrictive surgery may improve the metabolic situation
详细描述
In non-focal congenital hyperinsulinism (CHI) the current doctrine warrants subtotal pancreatic resection in all children who do not respond to medication. However, the rate of diabetes after these extensive resections is very high. In this study investigators show that a less aggressive approach may suffice to wean many children from all medication or to get them manageable medically.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with non-focal congenital hyperinsulinism
排除标准
- •patients with focal congenital hyperinsulinism
结局指标
主要结局
necessity of medication after restrictive surgery in congenital hyperinsulinism
时间窗: up to 3 years
次要结局
未报告次要终点
研究者
Prof. Winfried Barthlen
Professor of Pediatric surgery
University Medicine Greifswald
研究点 (1)
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