NL-OMON36358
Withdrawn
Not Applicable
Skeletal muscle characterization in frail elderly - Skeletal muscle in frailty
Medisch Universitair Ziekenhuis Maastricht0 sites50 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 50
- Status
- Withdrawn
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •frail male, non\-obese (BMI \<27 kg\*m\-2\) subjects aged 70\-90 years, with no history of participating in any regular exercise training program in the past 5 years, meeting 3 or more of these criteria: 1\) unintentional weight loss of 10% or more since age of 60 2\) self\-reported low usual energy level (3 on a 0\-10 scale), feeling unusually tired in the last month, or unusually weak in the last month; 3\) low energy expenditure, defined as being in the lowest quintile of energy expenditure measured using a six\-item version of the Minnesota Leisure Time Activity Questionnaire; 4\) slowness, defined as being in the lowest quintile of walking speed over a 4,57\-m distance; 5\) weakness, defined as being in the lowest quintile of hand grip strength measured using a handheld dynamometer.
- •Subjects will be considered non\-frail and, as such, eligible for inclusion in the study if 1 or less of the criteria is met (i.e. only non\-frail individuals in healthy elderly control group).
Exclusion Criteria
- •Exclusion criteria are: type I and type II diabetes, the use of anticoagulation, female sex, senile dementia, participation in any regular exercise program.
Outcomes
Primary Outcomes
Not specified
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