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Regional Differences in Human Immunodeficiency Virus (HIV) Testing

Completed
Conditions
HIV Seropositivity
CD4+ T Lymphocytopenia
Registration Number
NCT03158987
Lead Sponsor
Jena University Hospital
Brief Summary

This retrospective observational study aims at the examination of regional differences in the procedure of referral for serological HIV testing between eastern (new) and western (old) German federal states.

Detailed Description

Increasing incidence of HIV infections urges early recognition and timely introduction of therapy. Regional differences in referral approach and patient behavior are presumably associated with considerable delays in infection recognition and therapy onset. Comparison of records of new cases which were diagnosed in 2014 in several eastern federal states and a major western German city is expected to disclose whether the regionally preferred type of the primary care institution affects the time point of first diagnosis and the elapsed time since the emergence of the infection, as assessed by Cluster of Differentiation 4 positive (CD4+) lymphocyte counts and manifestation of clinical symptoms of immune deficiency.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
999
Inclusion Criteria
  • first-time HIV seropositivity
Exclusion Criteria
  • N/A

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Type of HIV-verifying medical institution1 day

Medical Institution (university hospital, general practitioner, specialized medical office) which has diagnosed HIV seropositivity for the first time

Secondary Outcome Measures
NameTimeMethod
CD4+ lymphocyte counts1 day

Number of CD4+ lymphocytes at the time of HIV diagnosis

Symptoms of AIDS-related diseases1 day

Presence of AIDS-related disease symptoms at the time of first HIV seropositivity diagnosis

Trial Locations

Locations (1)

University Hospital Jena

🇩🇪

Jena, Thuringia, Germany

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