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临床试验/CTRI/2025/07/089955
CTRI/2025/07/089955尚未招募3 期

A randomized controlled clinical study to evaluate the efficacy of tilanala pratisaraneeya kshara in the management of abhyantara arshas (2nd and 3rd degree internal haemorrhoids)

Dr Tanuja B M1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年7月15日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
reduction in number and size of pile mass after application of tilanala pratisaraneeya kshara

研究概览

简要总结

Arshas can be rationally correlated to haemorrhoids in Contemporary science. The term Arshas refers to illness which tortures the person like an enemy. Acharya Vagbhata describes Arshas as Mamsankura’s which is protruding out and obstructing the Guda marga1. As the age advances, the incidence rate increases in both male and female and atleast 50% are affected over the age of 50 years2. The prevalence rate of Haemorrhoids is 4.4% in the world, in about 10 million people3. The modern treatment modalities in internal haemorrhoids are Sclerotherapy, Rubber band ligation and Cryosurgery. Each procedure carries it’s own complications4. The Arshas which are Mrudu, Prasrutha, Avagadha and Uchrita should be treated by Pratisaraneeya Kshara5. Acharya Sushruta mentioned Kshara mahatva as Chedya, Bhedya, Lekhya, Tridoshagna6 and Kshara karma has a minimal invasive technique. Therefore, use of Kshara in the management of Arshas is the need of the hour. The drug Tilanala has been mentioned as one among the Kshara Panchaka in Kaiyadeva Nighantu7. Tilanala is annual plant which is available in all seasons8, where as Apamarga is seasonally available. Tilanala is easily available and cost effective. Tilanala is Madhura, Kasaya, Tikta, Katu rasa pradhana, Ushna virya, Madhura vipaka and it possesses the qualities of Vatahara, Vranahara, Sulaprashamana, Tridoshashamaka, hence it can be taken in Abhyantara Arshas (2nd & 3rd Degree Internal Haemorrhoids). Here an attempt is made to evaluate the efficacy of Tilanala Pratisaraneeya Kshara over Apamarga Pratisaraneeya Kshara in the management of Abhyantara Arshas (2nd & 3rd Degree Internal Haemorrhoids).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
30.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • All subjects were diagnosed and assessed thoroughly on the basis of Ayurvedic and modern signs and symptoms of internal haemorrhoids.
  • 2nd and 3rd degree internal haemorrhoids.
  • Maximum 3 pile masses.
  • Age between 30 to 65 years.

排除标准

  • 1st and 4th degree haemorrhoids Bleeding haemorrhoids Thrombosed pile mass Subjects associated with any other chronic systemic disorder Pregnant and lactating women Chronic alcoholic and chronic liver diseases Associated with any other Ano-rectal diseases Carcinoma of Ano-rectal diseases HIV, HCV and HBsAg positive patient Uncontrolled DM Uncontrolled Hypertension.

结局指标

主要结局

reduction in number and size of pile mass after application of tilanala pratisaraneeya kshara

时间窗: 45 days

次要结局

  • standardisation of preparation of tilanala pratisaraneeya kshara(1 month)

研究者

发起方
Dr Tanuja B M
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Tanuja B M

Shree Jagadguru gavisiddheshwara ayurvedic medical College Koppal

研究点 (1)

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