Diagnostic Accuracy of Serum Autotaxin Levels in Cholestasis of Pregnancy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Serum autotaxin levels in cholestasis of pregnancy
研究概览
简要总结
Intrahepatic cholestasis of pregnancy is the most common liver disease in pregnancy. It is is a pregnancy-specific liver disorder with onset mainly in the third trimester of pregnancy. ICP is characterized by pruritus, elevated serum fasting bile salts and transaminases and an increased risk of adverse fetal outcomes. Serum autotaxin levels were found highly sensitive and specific biomarker to to differentiate ICP from other pregnancy-related liver disorders or pruritic dermatoses. The purpose of the study is to determine the diagnostic accuracy of serum autotaxin activity in cholestasis of pregnancy.
详细描述
Collected data will enable us to compare serum autotaxin levels in cholestasis of pregnancy and healthy control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosed cholestasis of pregnancy patients
排除标准
- •acute or chronic liver disease
- •acute or chronic gallbladder disease
结局指标
主要结局
Serum autotaxin levels in cholestasis of pregnancy
时间窗: one year
次要结局
未报告次要终点
研究者
Hakan Erenel
MD, OB/GYN
Sisli Hamidiye Etfal Training and Research Hospital