Pre-Operative Imaging of Abdominal Wall Perforators Using CT Angiography

• Conditions: Breast Reconstruction

• Registration Number: NCT00748722
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

Abdominal donor-site flaps, including the transverse rectus abdominis musculocutaneous (TRAM) and deep inferior epigastric artery perforator flaps(DIEP), are standard in autologous breast reconstruction. With significant variation in the vascular anatomy of the abdominal wall, preoperative imaging is essential for preoperative planning and reducing intraoperative error.

The quest continues for optimal preoperative assessment. Computed tomographic angiography has recently been proposed as a noninvasive modality for this purpose. It provides the location of the perforator vessels, diameter and anatomic course in regards to the rectus muscle.

In this study we will perform preoperative lower abdominal computed tomographic angiography in DIEP flap breast reconstruction patients.

Detailed Description

Abdominal donor-site flaps, including the transverse rectus abdominis musculocutaneous (TRAM) and deep inferior epigastric artery perforator flaps(DIEP), are standard in autologous breast reconstruction. With significant variation in the vascular anatomy of the abdominal wall, preoperative imaging is essential for preoperative planning and reducing intraoperative error.

The quest continues for optimal preoperative assessment. Computed tomographic angiography has recently been proposed as a noninvasive modality for this purpose. It provides the location of the perforator vessels, diameter and anatomic course in regards to the rectus muscle.

In this study we will perform preoperative lower abdominal computed tomographic angiography in DIEP flap breast reconstruction patients.

We plan to study 20 patients, eligible for lower abdominal-based breast reconstruction.

Study Timeline

• Study First Submitted: 2008-07-15
• Status Verified: 2008-09
• Study Start: 2008-09
• Study First Submitted QC: 2008-09-07
• Last Update Submitted: 2008-09-07
• Study First Posted: 2008-09-09
• Last Update Posted: 2008-09-09
• Primary Completion: 2009-08
• Study Completion: 2009-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Female, age 18-60 years
• Appropriate for lower abdominal based breast reconstruction.
• Consented the use of CT Angiography

Exclusion Criteria

• Age under 18 years or over 60.
• Pregnant women
• Allergy to iodine

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1 year from starting date	1 year

Trial Locations

Locations (1)

Tel-Aviv Medical Center; 🇮🇱 Tel-Aviv, Israel