ISRCTN15233803Completed未知
Efficacy of Cerebrolysin treatment as an add-on therapy to thrombolysis and thrombectomy in severe stroke patients with unsuccessful reperfusion - a prospective single-center clinical study
niversity Hospital Centre Zagreb0 sites46 target enrollmentStarted: May 25, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 46
Study Overview
Brief Summary
2021 Results article in https://doi.org/10.1016/j.clineuro.2021.106767 (added 16/08/2021) 2021 Abstract results in https://doi.org/10.1177/23969873211034932 (added 14/06/2023)
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Aged 18 and over
- •2. Patients with acute ischemic stroke and initial NIHSS 8 or more
- •3. Treated in University Hospital Centre Zagreb with either thrombolytic therapy alone, or thrombolysis and thrombectomy, either proven by neuroimaging methods (MRI, MRA, DSA) or clinically (no change in NIHSS in the first 12 hours after recanalisation procedure) to fulfil the criteria of unsuccessful reperfusion
Exclusion Criteria
- •1. Haemorrhagic transition of a stroke on control CT scan after reperfusion therapy
- •2. Patients taking MAO inhibitors
- •3. Patients known to be allergic to the drug
- •4. Patients taking part in another trial
Investigators
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