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Clinical Trials/ISRCTN15233803
ISRCTN15233803
Completed
未知

Efficacy of Cerebrolysin treatment as an add-on therapy to thrombolysis and thrombectomy in severe stroke patients with unsuccessful reperfusion - a prospective single-center clinical study

niversity Hospital Centre Zagreb0 sites46 target enrollmentMay 25, 2020
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ConditionsAcute ischemic strokeCirculatory SystemStroke, not specified as haemorrhage or infarction

Overview

Phase
未知
Intervention
Not specified
Conditions
Acute ischemic stroke
Sponsor
niversity Hospital Centre Zagreb
Enrollment
46
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2021 Results article in https://doi.org/10.1016/j.clineuro.2021.106767 (added 16/08/2021) 2021 Abstract results in https://doi.org/10.1177/23969873211034932 (added 14/06/2023)

Registry
who.int
Start Date
May 25, 2020
End Date
January 1, 2020
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity Hospital Centre Zagreb

Eligibility Criteria

Inclusion Criteria

  • •1\. Aged 18 and over
  • •2\. Patients with acute ischemic stroke and initial NIHSS 8 or more
  • •3\. Treated in University Hospital Centre Zagreb with either thrombolytic therapy alone, or thrombolysis and thrombectomy, either proven by neuroimaging methods (MRI, MRA, DSA) or clinically (no change in NIHSS in the first 12 hours after recanalisation procedure) to fulfil the criteria of unsuccessful reperfusion

Exclusion Criteria

  • •1\. Haemorrhagic transition of a stroke on control CT scan after reperfusion therapy
  • •2\. Patients taking MAO inhibitors
  • •3\. Patients known to be allergic to the drug
  • •4\. Patients taking part in another trial

Outcomes

Primary Outcomes

Not specified

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