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Clinical Trials/NCT02034305
NCT02034305
Completed
Not Applicable

Pilot Study of Cough Peak Flow And Airway Clearance in Pediatric Patients With Neuromuscular Disease

University of Pittsburgh1 site in 1 country7 target enrollmentJanuary 2014
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ConditionsDuchenne Muscular Dystrophy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Duchenne Muscular Dystrophy
Sponsor
University of Pittsburgh
Enrollment
7
Locations
1
Primary Endpoint
Spontaneous cough clearance
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study is to determine whether physiologic measures (peak cough flow, measures of respiratory muscle strength including MIP, MEP ,SNIP, and spirometry) can predict spontaneous cough clearance (as measured by a nuclear medicine study) in children with neuromuscular disease. It will also determine whether airway clearance is augmented by high frequency chest wall oscillation.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
January 1, 2021
Last Updated
2 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Daniel J. Weiner

Associate Professor of Pediatrics

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • •Age 6-21; able to cooperate with study procedures
  • •Duchenne Muscular Dystrophy OR Becker Muscular Dystrophy

Exclusion Criteria

  • •Need for mechanical ventilation during the day
  • •Recent (within 2 weeks) lower respiratory tract infection

Outcomes

Primary Outcomes

Spontaneous cough clearance

Time Frame: Assessed at multiple time points over 30 minutes

Study Sites (1)

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