NCT02034305已完成不适用
Pilot Study of Cough Peak Flow And Airway Clearance in Pediatric Patients With Neuromuscular Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 7
- 试验地点
- 1
- 主要终点
- Spontaneous cough clearance
研究概览
简要总结
This study is to determine whether physiologic measures (peak cough flow, measures of respiratory muscle strength including MIP, MEP ,SNIP, and spirometry) can predict spontaneous cough clearance (as measured by a nuclear medicine study) in children with neuromuscular disease. It will also determine whether airway clearance is augmented by high frequency chest wall oscillation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 21 Years（Child, Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Age 6-21; able to cooperate with study procedures
- •Duchenne Muscular Dystrophy OR Becker Muscular Dystrophy
排除标准
- •Need for mechanical ventilation during the day
- •Recent (within 2 weeks) lower respiratory tract infection
结局指标
主要结局
Spontaneous cough clearance
时间窗: Assessed at multiple time points over 30 minutes
次要结局
未报告次要终点
研究者
Daniel J. Weiner
Associate Professor of Pediatrics
University of Pittsburgh
研究点 (1)
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