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Clinical Trials/NCT03357198
NCT03357198
Completed
Not Applicable

Correlation of Cough Peak Flow Measurement by an Electronic Handheld Spirometer Connected to the Endotracheal Tube and by the Intensive Care Unit Ventilator Flowmeter.

Centre Hospitalier Régional d'Orléans1 site in 1 country62 target enrollmentDecember 8, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Insufficiency
Sponsor
Centre Hospitalier Régional d'Orléans
Enrollment
62
Locations
1
Primary Endpoint
Correlation coefficient for the two CPF assessment methods, on extubation day
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Cough Peak Flow (CPF) seems to be an efficient tool to assess cough capacity for the intensive care unit (ICU) ventilated patient. CPF can be used in the ventilator weaning process, as reflecting the upper airways protection capacity.

CPF requires disconnection of the patient from the ICU ventilator, supplemental material (handheld spirometer, antibacterial filter) and an excellent synchronization between the specialized caregiver and the patient.

We aimed that CPF with the ventilator built-in flow-meter is correlated with CPF using a handheld flowmeter connected to the endotracheal tube.

Registry
clinicaltrials.gov
Start Date
December 8, 2017
End Date
August 29, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age \> 18 years
  • Mechanically ventilated patient \> 24 hours
  • Weaning ventilator phase (PEEP \< 9 cmH2O and Support \< 15 cm H2O)
  • Richmond Agitation Sedation Scale between -1 and +1
  • Patient's agreement to participate

Exclusion Criteria

  • Pregnant women
  • Bronchospasm
  • FiO2 \> 70%
  • Thoracic surgery \< 7 days
  • Abdominal surgery \< 7 days
  • Thoracic injury with rib fracture \< 21 days
  • Pneumothorax \< 24 hours

Outcomes

Primary Outcomes

Correlation coefficient for the two CPF assessment methods, on extubation day

Time Frame: Within 1 hour before mechanical ventilation termination (extubation)

Correlation coefficient for the two CPF assessment methods, on extubation day

Secondary Outcomes

  • 3. Correlation between the two CPF assessment methods the days before extubation(During the mechanical ventilation until 72 hours post extubation)
  • Assess the correlation between CPF and length of mechanical ventilation(During the mechanical ventilation until 72 hours post extubation)
  • Discriminatory power of CPF to predict successful weaning of mechanical ventilation, i.e. no reintubation within 72 hours after extubation, or unsuccessful weaning.(During the mechanical ventilation until 72 hours post extubation)

Study Sites (1)

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