Cough Peak Flow for Extubation Prediction
- Conditions
- Extubation in ICU Patients
- Registration Number
- NCT02847221
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
Successful weaning from mechanical ventilation in ICU patients depends on patient ability to breathe spontaneously and on cough efficiency. Previous studies found that cough peak flow (CPF) at 60 L/min threshold predicted extubation failure. These studies measured CPF using a dedicated flow-meter that required patient disconnection from the ventilator, limiting the generalizability of this procedure. This study aimed to predict extubation outcome in a consecutive series of patients by measuring CPF from the ventilator flow-meter. CPF measurements were done by freezing ventilator screen and scrolling the cursor to the maximal value of CPF during expiration and Tidal Volume (TV) in preceding inspiration.
The objective was to assess the performance of CPF to predict early extubation outcome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 92
- Age > 18 years
- Intubation > 24h
- Eligible for scheduled weaning trial and then scheduled extubation
- Mechanical ventilation from Evita XL ventilator (Dräger, Germany)
- Patient's agreement to participate
- Withdrawal decision of life supporting care
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early extubation success rate (EES rate) 48 hours Defining a relation between the CPF/TV ratio before extubation and early extubation success rate
- Secondary Outcome Measures
Name Time Method Scheduled weaning trial success rate 48 hours Defining a relation between the CPF/TV ratio before weaning trial and scheduled weaning trial success rate
Trial Locations
- Locations (1)
Medical Intensive care unit, Croix-Rousse Hospital. 103 Grande Rue de la Croix-Rousse
🇫🇷Lyon, France