Patient function & pain control after total knee replacement: Is it improved by use of peri-articular or intra-articular infiltration ?
Phase 4
Completed
- Conditions
- pain following total knee replacement surgerySurgery - Surgical techniquesAnaesthesiology - Pain managementMusculoskeletal - Osteoarthritis
- Registration Number
- ACTRN12615000488505
- Lead Sponsor
- Fremantle Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 142
Inclusion Criteria
adult patients waitlisted for primary total knee replacement for osteoarthritis.
Exclusion Criteria
allergy or intolerance to study drugs, known inability to receive spinal anaesthesia, and planned bilateral knee surgery.
secondary exclusion criteria: history of regular opioid use, concurrent psychiatric illness, serious medical comorbidities that might prolong hospital admission, and coagulation disorders
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method opioid consumption, assessed by patient medical charts and converted into standardised morphine equivalents.[during first 24 hrs postoperative];opioid consumption, assessed by patient medical charts and converted into standardised morphine equivalents.[over total inpatient admission];postoperative pain using a visual analogue scale[during postoperative day 1 and at discharge]
- Secondary Outcome Measures
Name Time Method oxford knee score[6 weeks postoperatively];knee flexion as assessed by doctor or physiotherapist on physical examination (no goniometer used)[at discharge, and at 6 weeks postoperatively];length of stay[from time of admission to hospital discharge.];haemoglobin drop, based on difference from routine preadmission preoperative blood test measurement to day 1 postoperative haemoglobin blood test measurement.[postoperative day 1]