The combined therapy with Olmesartan and Azelnidipin in the hypertensive patients with sleep apnea syndrome (SAS)
Not Applicable
- Conditions
- Sleep Apnea Syndrome
- Registration Number
- JPRN-UMIN000007171
- Lead Sponsor
- Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1) The patient who is taking azelnidipine or amlodipine 2) The patient who has critical liver disease. (AST or ALT is 100 or more IU/L) 3) The patient who has a critical renal disease (the patient under dialysis enforcement is included). (more than BUN 25mg/dL or more than serum creatinine 2.0mg/dL) 4) Pregnant or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure(Clinic BP,Home BP)
- Secondary Outcome Measures
Name Time Method PSG, AHI, noradrenalin, cortisol, Plasma aldosterone concentration, Plasma renin activity, ACTH, BNP,blood sugar level, renal function(the very-small-quantity albumin in urine, albuminuria, eGFR), Salt intake,HOMA-R, PAI-1, adiponectin