EAP-CP: Learning through Everyday Activities with Parents for infants at high risk of Cerebral Palsy in a low-income country

Not Applicable

Completed

• Conditions: cerebral palsy; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation; Neurological - Other neurological disorders

• Registration Number: ACTRN12616000653460
• Lead Sponsor: Queensland Cerebral Palsy and Rehabilitation Research Centre, The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-19
• Last Update Posted: 9 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 142

Inclusion Criteria

Infants must live in one of the study geographical areas, be aged 12-40 weeks C.A. and be diagnosed with cerebral palsy (CP) or assessed to be at high risk of cerebral palsy. Eligibility assessments will be videoed by the community coordinator and scored by certified General Movements (GMs) assessors. Infants will be determined at risk if:
- Aged 12-17 weeks corrected age (CA) with absent fidgety movements on the GMs assessment (98% predictive of CP). GMs is a feasible assessment in this context as it can be videoed by the community coordinator and scored by a general movements certified rater.
- Aged 18-40 weeks CA and score as ‘abnormal’ on the Hammersmith Infant Neurological Examination (90% predictive of CP)

Exclusion Criteria

Revised exclusion criteria:
(i) Infants diagnosed with neurodegenerative conditions
(ii) Infants with known or suspected congenital or chromosomal abnormalities which are likely to affect their neurodevelopmental outcome
(iii) Infants that are considered medically fragile

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infant functional abilities: change in normative scores on the mobility domain of the Pediatric Evaluation of Disability Inventory - Computer Adaptive Test (PEDI-CAT). This measure was the primary outcome a priori (ie before any recruitment commenced), however the mobility domain was selected as the primary outcome domain.[Baseline, and post-intervention (18 months CA)];Caregiver mental health: change in scores on the Depression, Anxiety, Stress Scale – Short Form (DASS) [Baseline, and post-intervention (infant aged 18 months CA)]