NCT05340218CompletedNot Applicable
"Análisis Longitudinal Del Habla y Seguimiento a Corto Plazo de Las Facultades Cognitivas de Personas Mediante Una Serie de Pruebas: Lista de Palabras CERAD, Repite Los dígitos en Orden Inverso, TMTA-B, Prueba Del Reloj, Fluidez fonémica, comprensión Verbal Relaciones semánticas, y semánticas Alternas".
Accexible1 site in 1 country196 target enrollmentStarted: January 1, 2019Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 196
- Locations
- 1
- Primary Endpoint
- Pre-post variability of normal, MCI and dementia at both points of the study.
Study Overview
Brief Summary
Validate speech analysis AI models:
- To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- To evaluate the correlation between automatically analyzed linguistic variables and a combination of standard measures of cognition.
- To assess short-term variability in language ability among older adults, and to assess which aspects of language vary during the study period.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 55 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Adult patients 55+ years of age with suspected MCI or diagnosis of dementia and obtains a score greater than 20 on the MMSE.
- •Patients must have agreed to participate in the study and have voluntarily signed the informed consent.
- •(Healthy) Participants without a diagnosis neurological, or psychiatric disorders. Or taking medication that can affect cognitive abilities.
Exclusion Criteria
- •To have received a diagnosis of a significant psychiatric disorder or other cognitive impairment not due to neurodegeneration.
- •To have significant vision problems that would affect the ability to perceive visual stimuli.
- •To have significant hearing problems that would affect the ability to understand verbal cues.
Outcomes
Primary Outcomes
Pre-post variability of normal, MCI and dementia at both points of the study.
Time Frame: Change from the baseline cognitive function at 9 months.
Through standard deviation of normal subjects, MCI and dementia, variations in language are measured by considering MMSE scores and the most significant variables of accexible's tests (image description test, phonetic verbal fluency test and semantic verbal fluency test).
Secondary Outcomes
- Correlation between cognitive tests and language variables obtained by the platform.(Every 6 to 9 months)
Investigators
Study Sites (1)
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