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Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study

Not Applicable
Completed
Conditions
Knee Osteoarthritis
Registration Number
NCT01188213
Lead Sponsor
Assaf-Harofeh Medical Center
Brief Summary

The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
  • radiographic confirmed knee OA according to the Kellgren & Lawrence scale
Exclusion Criteria
  • acute septic arthritis
  • inflammatory arthritis
  • any other type of arthritis
  • history of knee buckling or recent knee injury
  • lack of physical or mental bility to perform or comply with the treatment procedure
  • diabetes mellitus
  • fibromyalgia or other chronic pain syndromes
  • concurrent anti-coagulant/anti-platelet drugs
  • arthroscopy or intra-articular injections in the previous 3 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
WOMAC questionnaire
Secondary Outcome Measures
NameTimeMethod

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