An observational study of the correlation between hand grip strength and oxygen requirement after surgery under general anaesthesia

Completed

• Conditions: Intraoperative and postprocedural complications and disorders of ear and mastoid process, not elsewhere classified, (2) ICD-10 Condition: M96-M96||Intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified,

• Registration Number: CTRI/2023/12/060490
• Lead Sponsor: Dr Akshay A Kamath

Brief Summary

This study is an observational, single arm, multi-center study where we aim to objectively measure voluntary muscle control (hand grip strength) using a dynamometer to detect hypoventilation due to residual neuro-muscular blockade and its implication on post-operative oxygen requirement after general anaesthesia can be monitored. Primary outcome measures of hand grip strength (in kilogram) and peripheral saturation of oxygen (SpO2) will me measured half hourly till a duration of four hours and hourly till six hours. Secondary outcome measure of respiratory rate will also be simultaneously measured half hourly till a duration of four hours and hourly till six hours. Postoperative duration of oxygen requirement will also be noted.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Study Completion: 2024-12-31
• Last Update Posted: 2025-05-27

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. ASA (American society of Anaesthesiologists) 1 and 2 category patients 2) Adults aged 18-60 years of both genders 3) Elective surgeries of the non-dominant upper limb, head and neck under general anaesthesia 4) Surgical duration of greater than 3 hours.

Exclusion Criteria

1. Patients refusal to participate in the study 2) ASA 3 and above category patients 3) Those with preexisting neuromuscular disease 4) Obese patients with a body mass index greater than or equal to 30 kg/m2 5) Patients with a history of chronic pulmonary diseases 6) Patients with cardiac, hepato-renal diseases 7) Pregnant patients.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Hand – grip strength in kilogram	Pre-op (Baseline) | (Post-op) 30 min | 60 min | 90 min | 120 min | 150 min | 180 min | 210 min | 240 min | 300 min | 360 min
- Peripheral saturation of oxygen (SpO2)	Pre-op (Baseline) | (Post-op) 30 min | 60 min | 90 min | 120 min | 150 min | 180 min | 210 min | 240 min | 300 min | 360 min

Secondary Outcome Measures

Name	Time	Method
- Respiratory rate (RR)	- Duration of oxygen supplementation in hours

Trial Locations

Locations (3)

Durga Sanjeevani Manipal Hospital; 🇮🇳 Kannada, KARNATAKA, India

Government Wenlock District Hospital; 🇮🇳 Kannada, KARNATAKA, India

Kasturba Medical College, Attavar; 🇮🇳 Kannada, KARNATAKA, India

Durga Sanjeevani Manipal Hospital

🇮🇳Kannada, KARNATAKA, India

Dr Akshay A Kamath

Principal investigator

8105763251

akshayakamath43@gmail.com