Association Between Handgrip Strength and Small Airway Disease in Patients with Stable Chronic Obstructive Pulmonary Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COPD
- Sponsor
- Thammasat University
- Enrollment
- 64
- Locations
- 1
- Primary Endpoint
- Correlation between handgrip strength and small airway disease in COPD patients
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The goal of this observational study is to investigate the correlation between handgrip strength and small airway disease among patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:
• Is handgrip strength correlated with small airway disease in COPD patients? Participants will perform handgrip strength test and impulse oscillometry (IOS).
Detailed Description
This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and impulse oscillometry will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Small airway disease will be assessed using IOS.
Investigators
Narongkorn Saiphoklang, MD
Associate Professor
Thammasat University
Eligibility Criteria
Inclusion Criteria
- •COPD patients aged 40 years or older
- •Confirmed diagnosis by spirometry (post-bronchodilator FEV1/FVC \<0.7)
- •Smoking history 10 pack-years or more
Exclusion Criteria
- •COPD exacerbation within 3 months
- •Inability to perform handgrip strength test or impulse oscillometry
Outcomes
Primary Outcomes
Correlation between handgrip strength and small airway disease in COPD patients
Time Frame: At day 1 of the study
This correlation will be reported as correlation coefficient (R).
Secondary Outcomes
- The best cutoff value of handgrip strength for predicting small airway disease in COPD patients(At day1 of the study)