Association Between Handgrip Strength and Small Airway Disease in Patients with Stable Chronic Obstructive Pulmonary Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Correlation between handgrip strength and small airway disease in COPD patients
研究概览
简要总结
The goal of this observational study is to investigate the correlation between handgrip strength and small airway disease among patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:
• Is handgrip strength correlated with small airway disease in COPD patients? Participants will perform handgrip strength test and impulse oscillometry (IOS).
详细描述
This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and impulse oscillometry will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Small airway disease will be assessed using IOS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COPD patients aged 40 years or older
- •Confirmed diagnosis by spirometry (post-bronchodilator FEV1/FVC <0.7)
- •Smoking history 10 pack-years or more
排除标准
- •COPD exacerbation within 3 months
- •Inability to perform handgrip strength test or impulse oscillometry
结局指标
主要结局
Correlation between handgrip strength and small airway disease in COPD patients
时间窗: At day 1 of the study
This correlation will be reported as correlation coefficient (R).
次要结局
- The best cutoff value of handgrip strength for predicting small airway disease in COPD patients(At day1 of the study)
研究者
Narongkorn Saiphoklang, MD
Associate Professor
Thammasat University