ISRCTN15858091
Completed
Not Applicable
A randomised, controlled trial of interpersonal psychotherapy (IPT) and citalopram for depression in coronary artery disease
Montreal Heart Institute Research Center (Canada)0 sites280 target enrollmentAugust 17, 2005
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Major depression
- Sponsor
- Montreal Heart Institute Research Center (Canada)
- Enrollment
- 280
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Persons of either sex in age groups: 18 years and above.
- •1\. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM\-IV) diagnosis of current major depressive episode based on the Structured Clinical Interview for Depression (SCID) with at least 4 weeks duration
- •2\. Baseline score greater than 19 on the centralized, telephone\-administered 24\-item, Hamilton Depression Rating Scale (HAM\-D)
- •3\. Evidence of coronary artery disease (CAD) based on hospital chart evidence of a previous hospitalization for acute myocardial infarction, or coronary angiographic evidence of greater than 50% blockage in at least one major coronary artery, or prior revascularization
- •4\. Stable CAD based on physician?s clinical judgement
- •5\. Provision of informed consent
Exclusion Criteria
- •1\. Less than 18 years of age
- •2\. Coronary bypass surgery planned during the next 4 months
- •3\. Canadian Cardiovascular Society Angina Class (CCS) \= 4
- •4\. SCID documented bipolar disorder, major depression with psychotic features or evidence of substance abuse or dependency during the previous 12 months
- •5\. Serious suicide or risk based on clinical judgment
- •6\. Use of anti\-depressants, lithium or anti\-convulsants for mood disorder
- •7\. Currently undergoing any form of psychotherapy
- •8\. Absence of response to a previous adequate trial of citalopram or IPT
- •9\. Two previous unsuccessful trials of treatment for depression for the index episode
- •10\. Lifetime history of early termination (less than 8 weeks) of citalopram because of adverse events or side\-effects
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
A randomised clinical trial of interpersonal social rhythms psychotherapy in young people with bipolar disorder.Bipolar disorderNeurological - Other neurological disordersACTRN12605000722695Health Research Council of New Zealand120
Completed
Not Applicable
Randomised controlled trial of group Interpersonal PsychoTherapy with depressed community members in a rural township in Huairou County, BeijingMajor and minor depression as defined by DSM-IV diagnostic criteriaMental and Behavioural DisordersDepressionISRCTN40122815Beijing Suicide Reseach and Prevention Center (China)120
Completed
Not Applicable
Controlled Clinical Trial of Interpersonal Psychotherapy Versus Psychoeducation Program for Pregnant Women with Psychiatric Disorders during Perinatal Periodpsychiatric disorderJPRN-UMIN000023166Hyogo College of Medicine60
Recruiting
Not Applicable
Evaluation of short term support for emergency department attendees who present with moderate and high levels of stress: a pilot studyModerate and high levels of non specific psychological distress identified by the Kessler Psychological distress scales (K10)Mental Health - DepressionMental Health - AnxietyPublic Health - Health promotion/educationACTRN12614000031662The Prince Charles Hospital90
Recruiting
Not Applicable
A randomized controlled trial of brief interpersonal psychotherapy for Japanese women with perinatal depression.JPRN-UMIN000043822Hyogo College of Medicine50