Chinese Multi-provincial Cohort Study-Beijing Project
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 3,000
- Locations
- 3
- Primary Endpoint
- All fatal and nonfatal acute coronary and stroke events
Study Overview
Brief Summary
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health problems through repeat examinations. Exam 0 to Exam 3 have been conducted during 1992 to 2012. Exam 4 is scheduled in 2020.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 60 Years to 100 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Participants from CMCS-Beijing
- •sign the informed consent
Exclusion Criteria
- •participanting in clinical trials
Outcomes
Primary Outcomes
All fatal and nonfatal acute coronary and stroke events
Time Frame: From date of enrollment until the date of first documented event or date of cardiovascular death, whichever came first, assessed at least 5 years
Acute coronary heart disease events included acute myocardial infarction, sudden death, and other coronary deaths. Acute stroke events included subarachnoid hemorrhage, intracerebral hemorrhage, or cerebral infarction.
Secondary Outcomes
- Cognitive dysfunction(From date of enrollment until date of first documented event, assessed at least 5 years)
- Valvular disease(From date of enrollment until the date of first documented event or date of valvular disease death, whichever came first, assessed at least 5 years)
- New-onset of stroke(From date of enrollment until the date of first documented event or date of stroke death, whichever came first, assessed at least 5 years)
- Total death(From date of enrollment until date of death from all cause, assessed at least 5 years)
- Olfactory Disorders(From date of enrollment until date of first documented event, assessed at least 5 years)
- New-onset of coronary events(From date of enrollment until the date of first documented event or date of CHD death, whichever came first, assessed at least 5 years)