Relationships between oral and gastrointestinal sensitivities in response to fat and protein, and body mass index (BMI).

Not Applicable

Completed

• Conditions: utrition; Gastrointestinal motor and hormonal function; Oral cavity taste receptor sensitivity; Nutrition; Diet and Nutrition - Other diet and nutrition disorders; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12612000942853
• Lead Sponsor: Dr Natalie Luscombe-Marsh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-09-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

Males with a BMI between 18-35 kg/m2.

Weight stable (<5% fluctuation in body weight in previous 3 months).

Exclusion Criteria

Significant gastrointestinal symptoms, disease, or surgery

Use of prescribed or non-prescribed medications (including vitamins and herbal supplements) which may effect energy metabolism, gastrointestinal function, body weight, or appetite (eg. domperidone and cisapride, anticholinergic drugs (eg. atropine), metoclopramide, erythromycin, hyoscine, orlistat, green tea extracts, astragalus, St. johns wort etc.)

Lactose intolerant or other food allergies (particularly MSG); intolerance or allergy to paracetamol

Current, recurring or chronic rhinitis

Current gallbladder or pancreatic disease; diabetes mellitus; epilepsy; cardiovascular or respiratory diseases; any other illnesses as assessed by the investigator (including chronic illnesses not explicitly listed above)

Individuals with low ferritin levels or who have donated blood in the 12 weeks prior to taking part in the study

Individuals with blood glucose and/or glycated haemoglobin outside the normal ranges.

High performance athletes

Current intake of >2 standard drinks on >5 days per week

Current smokers of cigarettes/cigars/marijuana

Current intake of any illicit substance

Experience claustrophobia in confined spaces

Unable to tolerate nasogastrointestinal tube, or to comprehend study protocol

Study & Design

• Study Type: Interventional
• Study Design: Not specified