Efficacy of local infiltration tramadol (Transversus abdominis plane block technique) versus preemptive intravenous tramadol on postoperative pain after open appendectomy: a prospective randomized controlled trial

Phase 4

Completed

• Conditions: Post operative pain control in appendicitis patients who undergo open appendectomy; Appendectomy; Appendicitis; Local; Tramadol

• Registration Number: TCTR20230111008
• Lead Sponsor: Police general hospital,Bangkok

Brief Summary

ocal tramadol with transversus abdominis plane block technique is an alternative for postoperative pain reduction after open appendectomy and decrease postoperative opioid consumption compared with intravenous tramadol without any complications

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-10-01
• Study Start: 2023-01-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

preoperative and postoperative diagnosis of acute appendicitis who undergo open appendectomy under general anesthesia

Exclusion Criteria

American association of Anesthesiologist (ASA) classification above3, allergy to tramadol or opioid derivatives, unable follow instruction to evaluated pain score, patient with history of chronic pain/ long term opioid used, contraindication to general anesthesia such as malignant hyperthermia or airborne disease and patients who undergo appendectomy with delay suture.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pain at rest and activity 24hours Visual analogue scale

Secondary Outcome Measures

Name	Time	Method
postoperative opioid consumption 24hours Milligram per kilogram,Complications 24hours Side effect (N/V,surgical site infection),Lenght of hospital stay at least 24 hours Hours