Eye movement desensitization and reprocessing therapy in early psychosis

Not Applicable

Completed

• Conditions: Schizophrenia, schizotypal and delusional disorders; Mental and Behavioural Disorders

• Registration Number: ISRCTN16262847
• Lead Sponsor: ancashire Care NHS Foundation Trust

Brief Summary

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33225584/ (added 16/04/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-28
• Study Completion: 2022-05-31
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Aged at least 16 years
2. Capacity and willingness to provide informed consent
3. ICD diagnosis of schizophrenia-spectrum disorders (ICD codes F20, F22, F23, F25, F28, F29; ICD-11 codes 6A20, 6A21, 6A23, 6A24, 6A2Y,6A2Z) or LCFT EIS psychosis criteria, operationally defined using the Positive and Negative Syndrome Scale (PANSS) and/or the psychosis transition criteria of the Comprehensive Assessment of At-Risk Mental States (CAARMS)
4. In contact with mental health services, and have an assigned care-coordinator
5. Within 3 years from psychosis onset
6. Judged by the assigned care-coordinator/responsible clinician as clinically stable (no treatment change in the previous month)
7. Reporting at least 1 traumatic event on the Trauma Screening Questionnaire (TSQ), and at least subsyndromal post-traumatic symptoms in the previous week (scores > 0 on items 3_1 to 3_5 of the TSQ)
8. Meet a criterion level of positive symptoms severity, indicated by a score > 3 (symptom present) on the delusions (P1), hallucinations (P3), grandiosity (P5) or suspiciousness (P6) items of the PANSS in the previous week

Exclusion Criteria

1. Primary diagnosis of substance/alcohol dependence, intellectual disability or cognitive dysfunction, as provided by the participant care-coordinator/clinical team
2. Non-English speaking or requiring an interpreter for the intervention (the therapy and assessment battery at present can only be delivered in English)
3. Receipt of EMDR from a qualified psychological therapist in accordance with NICE guidelines for PTSD in the past 12 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified