Computerized Working Memory Training in Adults With Substance Abuse and Executive Function Deficits: A Randomised Controlled Trial.
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).
研究概览
简要总结
The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.
详细描述
The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Treatment seeking adults with substance abuse and executive function deficits.
排除标准
- •Acute intoxication or abstinence symptoms of any substance.
- •Psychosis.
研究组 & 干预措施
Cogmed working memory training
30-40 minutes of Cogmed computerized working memory training 3-5 days a week for 5-8 weeks. Every training session consists of a set of visual- and verbal working memory tasks that are trained on during the session.
干预措施: Computerized Cogmed working memory training (Behavioral)
结局指标
主要结局
Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).
时间窗: Baseline and at 25 weeks
次要结局
- Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index.(Baseline and at 25 weeks)
- Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II).(Baseline and at 25 weeks)
- Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index.(Baseline and at 25 weeks)
- Change from baseline in verbal working memory measured with performance on Digit span.(Baseline and at 25 weeks)
- Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale.(Baseline and at 25 weeks)
- Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales.(Baseline and at 25 weeks)
- Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A).(Baseline and at 25 weeks)
- Change from baseline in visual working memory measured with performance on Span board.(Baseline and at 25 weeks)
- Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II).(Baseline and at 25 weeks)
- Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version).(Baseline and at 25 weeks)
研究者
Rickard Ahlberg
Clinical psychologist, doctoral student.
Örebro Läns Landsting