Immediate-access Arteriovenous Versus Standard Arteriovenous Grafts in Hemodialysis Patients: A Randomized Clinical Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hemodialysis Access Failure
- Sponsor
- Egyptian Biomedical Research Network
- Enrollment
- 477
- Locations
- 2
- Primary Endpoint
- Success rate
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Arteriovenous fistulae (AVF) are considered the main access for hemodialysis (HD). Arteriovenous grafts (AVGs) are an alternative access modality in patients with exhausted native venous access. Immediate-access arteriovenous grafts (IAAVGs) is a new modality in which dialysis can be started immediately to avoid complications of central venous catheters.
Detailed Description
The study aimed to evaluate and compare patency rate and complications of standard arteriovenous grafts (SAVGs) and immediate-access arteriovenous grafts (IAAVGs) in end stage renal disease (ESRD) patients for one year after the intervention. Patients were randomly divided into two groups: SAVGs group and IAAVGs group. Patients with ESRD with no chance for native AVF were examined clinically and by duplex ultrasonography preoperatively. Follow up was for one year. Primary end points were the success rate, complications rate (hematoma, pseudo-aneurysm, graft site infection, systemic bacteremia), time of first cannulation. Secondary end points were primary and secondary patency within one year.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult hemodialysis patients
Exclusion Criteria
- •Significant cardiorespiratory comorbidities.
- •Peripheral vascular disease.
- •Pregnancy or lactation.
- •Severe bleeding disorders.
Outcomes
Primary Outcomes
Success rate
Time Frame: 24 hours
successful graft procedure
Primary Patency
Time Frame: 1 year
Patency of hemodialysis access
Secondary Outcomes
- Complications rate(1 year)