Uremic Toxins in the Intensive Care Units (ICU): Patients With Lactate Acidosis

Not Applicable

Completed

• Conditions: Acute Renal Failure
• Interventions: Procedure: Dialysis during 6 hours; Procedure: Dialysis during 8 hours; Procedure: Dialysis during 4 hours

• Registration Number: NCT00752453
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with lactate acidosis. The sampling of blood and dialysate will be done during dialysis with different durations (4, 6 and 8 h)

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-31
• Study First Submitted: 2008-09-12
• Study First Submitted QC: 2008-09-12
• Study First Posted: 2008-09-15
• Primary Completion: 2013-10-04
• Study Completion: 2013-12-31
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-14
• Last Update Posted: 2022-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• Includes ICU patients with lactate acidosis with acute renal failure

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
2	Dialysis during 6 hours	Dialysis during 6 hours
3	Dialysis during 8 hours	Dialysis during 8 hours
1	Dialysis during 4 hours	Dialysis during 4 hours

Primary Outcome Measures

Name	Time	Method
Toxin removal	During dialysis

Trial Locations

Locations (1)

University Hospital Ghent; 🇧🇪 Ghent, Belgium