Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis

Not Applicable

Withdrawn

• Conditions: Renal Failure; Multi Organ Failure
• Interventions: Procedure: Dialysis during 4 hours; Procedure: Dialysis during 8 hours; Procedure: Dialysis during 6 hours

• Registration Number: NCT00752245
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with sepsis/multi-organ failure. The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-31
• Study First Submitted: 2008-09-12
• Study First Submitted QC: 2008-09-12
• Study First Posted: 2008-09-15
• Primary Completion: 2013-10-04
• Study Completion: 2013-10-04
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-14
• Last Update Posted: 2022-12-15

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• ICU patients with sepsis/multi-organ failure with acute renal failure

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	Dialysis during 4 hours	Dialysis during 4 hours
3	Dialysis during 8 hours	Dialysis during 8 hours
2	Dialysis during 6 hours	Dialysis during 6 hours

Primary Outcome Measures

Name	Time	Method
Registration of toxin removal efficiency	During dialysis

Trial Locations

Locations (1)

University Hospital Ghent; 🇧🇪 Ghent, Belgium