Pharmacokinetics of antituberculosis drugs in Thai populatio

• Conditions: Thai adults with active TB; pharmacokinetics; adult TB; pharmacogenetics; first-line antituberculosis drugs; second-line antituberculosis drugs; tuberculosis

• Registration Number: TCTR20210323004
• Lead Sponsor: Graduated School, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-23
• Study Completion: 2022-04-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Adults, males or females who are 18 - 65 years old.
2. Diagnosed with active TB
3. Voluntarily sign and date an informed consent

Exclusion Criteria

1. Diagnosed with acute hepatitis or cirrhosis
2. Pregnant or breastfeeding

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tmax, Cmax, AUC 0, 1, 2, 4, 6, 8, 12 hrs liquid chromatography mass spectrometry

Secondary Outcome Measures

Name	Time	Method
genotype variants 1 hr after dosing MassARRAY