"Fight-or-flight" Versus "Tend-and-befriend" Response to Behavioral and Pharmacological Interventions in Patients With Borderline Personality Disorder - Part I
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 196
- Locations
- 1
- Primary Endpoint
- empathy
Study Overview
Brief Summary
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior in BPD patients.
Detailed Description
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior, such as empathy, in BPD patients and whether this "fight-or-flight" pattern is also seen in other relevant aspects of social behavior, such as sharing and punishment behavior. To induce social exclusion all participants will play cyberball, either the exclusion condition or the (over)inclusion condition before testing
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 60 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •female patients with BPD and healthy control women, matched for age, body mass index, and education
Exclusion Criteria
- •physical illness
Arms & Interventions
exclusion BPD
cyberball exclusion condition - BPD patients
Intervention: inclusion condition (Behavioral)
over-inclusion BPD
cyberball over-inclusion condition - BPD patients
Intervention: inclusion condition (Behavioral)
exclusion healthy controls
cyberball exclusion condition - healthy controls
Intervention: inclusion condition (Behavioral)
over-inclusion healthy controls
cyberball over-inclusion condition - healthy controls
Intervention: inclusion condition (Behavioral)
Outcomes
Primary Outcomes
empathy
Time Frame: 30 minutes after cyberball
Multifaceted Empathy Test
Secondary Outcomes
- sharing behavior: amount of monetary units (max 30) shared with co-player(directly after cyberball)
Investigators
Katja Wingenfeld
Principal Investigator
Charite University, Berlin, Germany