se of Steroids for postoperative keratoplasty for fungal keratities
- Conditions
- Health Condition 1: H160- Corneal ulcer
- Registration Number
- CTRI/2022/06/043019
- Lead Sponsor
- V Prasad Eye Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Cases with microbiologically confirmed fungal keratitis undergoing therapeutic keratoplasty for worsening of infection.
2.Size of infiltrate less or equal to 10 mm.
3.Intraoperative no evidence of residual infection
4.Immediate Post operative anterior chamber formed and no clinical evidence of infection
5.Use of MK medium corneal tissue of any grade with or with out intact epithelium
6.Intraoperative Preserved lens
7.Ready to give consent
8.Consent for regular follow-up
9.More than 18 years
10.Surgery performed by surgeons with experience of performing more than 20 TPK.
1.Any evidence of intraop or clinical post-operative infection
2.Size of infiltrate > 10 mm
3.Not willing to come for regular follow-up or admission or giving consent
4.Disorganized anterior chamber
5.Posterior segment involvement as confirmed on Echoes in the posterior segment on B scan
6.Intraoperative presence of retero-iris and lens exudates.
7.Presence if corneal perforation before the surgery
8.Presence of uncontrolled diabetes or any other cause of decreased imununity.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Graft survival rate at 6 months in both the groups and compared.Timepoint: 3, 7,14, 30 days, 3 , 6 months and 1 year of follow-up
- Secondary Outcome Measures
Name Time Method umber of patients having recurrence of similar infection with in 2 weeks of surgery.Timepoint: 3, 7,14, 30 days, 3 , 6 months and 1 year of follow-up