Efficacy of tobacco cessation for improving oral diseases - multicentre trial
- Conditions
- Oral DiseasesPeriodontitis Patients for implant treatment Oral mucosal diseases (nicotine stomatitis, oral leukoplakia, erythloplakia and oral lichen planus)
- Registration Number
- JPRN-UMIN000024884
- Lead Sponsor
- Tobacco Cessation Intervention Study Team for Oral Diseases (TISOD)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 812
Not provided
Less than 20 years old Already having any cessation intervention Having had periodontal treatment within 6 months Periodontitis patients who have anti-inflammatory drug or steroid use Patients for implant treatment; N/A Oral mucosal diseases; have had surgical resections before or other interventional treatments In case of use of nicotine replacement therapy (NRT);already have a prescription of NRTs or medicines, pregnant and breastfeeding women, has unstable angina pectoris, in the immediate (within 3 months) past myocardial infarction period, have serious arrhythmias, post-percutaneous coronary intervention (PCI), post-coronary artery bypass graft (CABG), early period of recovery from cerebrovascular disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical improvement of each disease (12 months after the treatment) Periodontitis- Probing pocket depth and clinical attachment level of two sites with the deepest periodontal pocket (6 mm or more) Implant- one-year implant survival and per-implant marginal bone loss the day after implant placement and after 1 year measured by a standardized X-ray photo Oral mucosal diseases-size reduction (major x minor axis /mm) at a predominant site for non-surgical group and recurrence rate for surgical group
- Secondary Outcome Measures
Name Time Method Tobacco abstinence rate at each observation period at 3, 6, 12, 24 months for each disease group