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Adjuvant chemotherapy in the patients with stage II colon cancer that have MSI-H status and poor prognostic factors : to give or not to give?

Not Applicable
Recruiting
Conditions
To find out if the patients with stage II colon cancer that have MSI&#45
H and poor prognostic factors gain the survival benefit (disease&#45
free and overall survival) of adjuvant chemotherapy or not
Colon cancer
Stage II
Poor prognostic factor
MSI
adjuvant chemotherapy
Registration Number
TCTR20180329003
Lead Sponsor
Ratchadapiseksompoch
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

-Patients with pathologically confirmed stage II colon cancer with poor prognostic factors
-Age > 18 years
-Available tissue specimen for MMR testing

Exclusion Criteria

-Not available tissue specimen for MMR testing

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disease free survival, overall survival 5 years after the operation Kaplan meier method
Secondary Outcome Measures
NameTimeMethod
complication from treatment 6 months after the adjuvant chemotherapy percentage
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