Improvement in Cognitive functioning in Patients with Schizophrenia after cognitive retraining.
- Conditions
- Health Condition 1: null- Schizophrenia
- Registration Number
- CTRI/2018/05/014095
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Male or female between 18-45 years of age
Meeting the DSM-5 clinical criteria for schizophrenia (APA, 2013)
Patients currently stabilized on same antipsychotics for a period of at least 6 weeks
Patients or primary caregiver with capacity and willingness to give informed consent.
Both in-patients and out-patients
Having basic familiarity & comfort with using computers
Both Right and Left Handed
Education up to Primary level
Presence of past or current co-morbid Axis I disorders including substance abuse/dependence (other than caffeine or nicotine)
Any history of seizure EXCEPT those therapeutically induced by ECT
History suggestive of any neurological or progressive neurological condition.
Having Colour blindness or Blindness
Hearing impairment
Non-consenting individuals
Visual or motor disability which may hinder use of computers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Cognitive function (Time Frame: At baseline, post-intervention and at 3 months follow up.) <br/ ><br>-Clinical improvement of cognitive symptoms relative to pre-treatment baseline (Time Frame: At baseline, post-intervention and at 3 months follow up). <br/ ><br>-WHODAS II (Time Frame: At baseline, post-intervention and at 3 months follow up). <br/ ><br>Timepoint: The short term effectiveness would be measured immediately after the completion of the rehabilitation program at 9 weeks
- Secondary Outcome Measures
Name Time Method Clinical improvement of negative symptoms (PANSS) relative to pre-treatment baseline. <br/ ><br>Global clinical improvement on Clinical global Impression <br/ ><br>Timepoint: The short term effectiveness would be measured immediately after the completion of the rehabilitation program in the 9th week, after completion of the retraining.