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临床试验/NCT01735773
NCT01735773已完成不适用

The Relationship of Prohepcidin Levels With Anemia and Inflammatory Markers in Non-diabetic Uremic Patients: A Controlled Study

Haseki Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2010年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
25
试验地点
1
主要终点
prohepcidin level

研究概览

简要总结

The investigators aimed to study the effect of prohepcidin levels on hematologic parameters and inflammatory markers in non-diabetic uremic patients. The investigators selected three groups of patients: Hemodialysis group, peritoneal dialysis group and the group with stage 4 chronic kidney disease. A control group was formed from healthy volunteers also. Each group has been planned to be formed of about 25 patients. Diabetic patients were excluded. Prohepcidin, hsCRP, IL-6, fibrinogen have been planned to be studied besides other routine biochemical analysis including hematological ones.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • hemodialysis and peritoneal dialysis patients who had been on dialysis therapy for more than 3 months,
  • age between 18-80 years,
  • patients with creatinine clearance between 15-30 ml/min.

排除标准

  • age less than 18 or more than 80,
  • diabetic patients,
  • current active infectious or inflammatory disease.

结局指标

主要结局

prohepcidin level

时间窗: Six months

Prohepcidin levels will be compared with other inflammatory markers.

次要结局

  • Anemia and inflammatory markers(Six months)

研究者

发起方
Haseki Training and Research Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

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