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Clinical Trials/NCT04102319
NCT04102319
Unknown
Not Applicable

Association Between Hepcidin, Haemoglobin Level and Iron Status in Stage 4 Chronic Kidney Disease Patients With Anaemia

Assiut University0 sites64 target enrollmentOctober 1, 2019
ConditionsCKD Stage 4

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
CKD Stage 4
Sponsor
Assiut University
Enrollment
64
Primary Endpoint
relation between serum hepcidin level and ESR ckd stage 4
Last Updated
6 years ago

Overview

Brief Summary

The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.

Registry
clinicaltrials.gov
Start Date
October 1, 2019
End Date
December 1, 2023
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Deiaaeldeen Masaoud Sadeq Mohammed

Dr

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Adult patients (\>18 years) with anaemia who had CKD stage 4 with glomerular filtration rate (GFR) 15-29 ml/min/1.73 m2

Exclusion Criteria

  • Subjects with blood transfusion within the preceding 3 months. myocardial infarction (MI) history within the preceding 3 months, surgical history within the preceding 3 months, malignancy. Advanced liver cirrhosis. uncontrolled diabetes

Outcomes

Primary Outcomes

relation between serum hepcidin level and ESR ckd stage 4

Time Frame: at study entry and then again after 3 months

measure strength of relation, r, between levels of serum hepcidin and ESR, an inflammation marker

relation between serum hepcidin and serum ferritin levels

Time Frame: at study entry and then again after 3 months

measure strength of relation, r, between levels of hecidin and ferritin

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