Serum Hepcidin, Haemoglobin Level and Iron Status in Chronic Kidney Disease Patients (CKD) With Anaemia

• Conditions: CKD Stage 4

• Registration Number: NCT04102319
• Lead Sponsor: Assiut University

Brief Summary

The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-09
• Study First Submitted: 2019-09-19
• Study First Submitted QC: 2019-09-22
• Last Update Submitted: 2019-09-22
• Study First Posted: 2019-09-25
• Last Update Posted: 2019-09-25
• Study Start: 2019-10-01
• Primary Completion: 2022-10-01
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Adult patients (>18 years) with anaemia who had CKD stage 4 with glomerular filtration rate (GFR) 15-29 ml/min/1.73 m2

Exclusion Criteria

• Subjects with blood transfusion within the preceding 3 months. myocardial infarction (MI) history within the preceding 3 months, surgical history within the preceding 3 months, malignancy. Advanced liver cirrhosis. uncontrolled diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
relation between serum hepcidin level and ESR ckd stage 4	at study entry and then again after 3 months	measure strength of relation, r, between levels of serum hepcidin and ESR, an inflammation marker
relation between serum hepcidin and serum ferritin levels	at study entry and then again after 3 months	measure strength of relation, r, between levels of hecidin and ferritin