Pilot study to determine clock-related nonvisual effects of light on alertness and metabolism

Withdrawn

Conditions: biologische klok, alertheid, slaperigheid, metabolisme
biological clock

Registration Number: NL-OMON44192

Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 8

Inclusion Criteria

Gezonde mannelijk proefpersonen
Leeftijd: 20-30
Schriftelijke ondertekening van het toestemmingsformulier

Exclusion Criteria

Colour blindness
Sleeping problems
Usage of (recreational) drugs
Smoking
Moderate to high levels of caffeine intake
Diabetic disease
Shift work scheduled 3 months prior to participation
Travel over 2 or more time zones prior to participation
PSQI>5
Epworth Sleepiness Scale >10
Glasses
Use of photosensitizing medication or sleep medication
Use of melatonin

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are melatonin rhythms (saliva samples) and core body<br /><br>temperature (CBT) to test whether a short FD protocol can be used as an<br /><br>alternative to a multiple-week FD protocol in disentangling homeostatic and<br /><br>circadian components affecting alertness, sleep, heart rate, metabolism and<br /><br>body temperature. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are subjective sleepiness, subjective and objective<br /><br>sleep quality, metabolic rate, heart rate, core body temperature and skin<br /><br>temperature, to investigate whether light can affect alertness (and whether<br /><br>this effect depends on the circadian clock).</p><br>