Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test
- Conditions
- Coronary Arteriosclerosis
- Registration Number
- NCT00352937
- Lead Sponsor
- Providence VA Medical Center
- Brief Summary
To compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial perfusion imaging in detecting coronary artery disease (CAD) in patients without a previously established diagnosis of CAD.
- Detailed Description
Nuclear stress testing is currently the established non-invasive modality in detecting flow-obstructing coronary artery disease (CAD).
Recently, multi-detector CT (MDCT) has emerged as a new modality that offers a non-invasive means to directly visualize coronary anatomy and any CAD. Studies have shown that MDCT has excellent sensitivity and a high negative predictive value in detecting significant CAD.
The purpose of this study is to compare MDCT with nuclear stress testing for detecting CAD in previously undiagnosed patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 98
- Referred for a clinical indicated stress SPECT MPI
- Adequate IV access in both arms
- History of coronary angioplasty or stent placement
- History of coronary bypass surgery
- Angiographic history of flow-limiting CAD
- Documented history of elevated cardiac markers
- Documented history of injury or infarct on ECG
- Absence of sinus rhythm
- Current history of renal insufficiency
- Known allergy to contrast dye
- Pregnant
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Calcium score 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Providence Veterans Affairs Medical Center
🇺🇸Providence, Rhode Island, United States