Effect of axillary hair epilation therapy using a Diode laser with a combined wavelength of 810, 940, and 1,060 nanometers in static mode compared to dynamic mode on sweat productio

Phase 4

Active, not recruiting

• Conditions: Axillary hyperhidrosis in volunteers with unwanted axillary hairs after hair epilation therapy using a Diode laser; Hair removal laser, Axillary hair, Hyperhidrosis

• Registration Number: TCTR20231110004
• Lead Sponsor: Faculty of Medicine, Srinakharinwirot University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-11-10
• Last Update Posted: 19 August 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

1. Patient with unwanted axillary hairs who want to treat with hair removal laser, 2. Age between 18-45 years old, 3. Willing to participate the study, 4. Able to come follow the appointment

Exclusion Criteria

1. Presence of focal, visible sweating for at least 6 months without any obvious cause in addition to the presence of at least 2 of the following characteristics: Bilateral and relatively symmetrical
(Affects daily activities, More than one time per week, Younger than 25 years old at the beginning of hyperhidrosis, Positive family history, Absence of night sweats or sweating during sleeping periods), 2. Comorbidities which can cause secondary hyperhidrosis (Heart diseases, Diabetes, Thyroid diseases, Pheochromocytoma), 3. Currently has any kind of malignant cancers, 4. Medications which can cause secondary hyperhidrosis within 15 days, 5. Have any history of undergoing axillary gland excision, liposuction, sympathectomy and subcutaneous curettage, 6. History of currently using Aluminium Chloride solution for hyperhidrosis, 7. History of undergoing any laser at axilla within 6 months, 8. History of Botulinum toxin A injection or Iontophoresis or Microwave therapy at axilla within 12 months, 9. Pregnancy, 10. Menopause, 11. Heat-stimulated diseases or Disease with Koebners phenomenon eg. Psoriasis, Lichen planus, Vitiligo, Halo nevus, 12. Any skin diseases in axillary area eg. eccrine nevus, and infection at axillary area

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sweat production Day 0, week 4, 8, 12, 18, 24 Gravimetry, Iodine starch test with SIVS score, and HDSS score

Secondary Outcome Measures

Name	Time	Method
Malodor Day 0, week 4, 8, 12, 18, 24 Modified axillary malodor score,Adverse effects Day 0, week 4, 8, 12, 18, 24 Observation,Patient's satisfaction week 24 10-point scale