Evaluation of the Efficacy and Safety of Topical Adiponectin Peptides on Hair Growth and Preventing Hair Loss
- Conditions
- Diseases of the skin and subcutaneous tissue
- Registration Number
- KCT0003559
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 60
• volunteer in writing to participate who understand the need and process of clinical trials
• Among the men aged 18 to 49, Hamilton-Norwood class III, IV, V
• Volunteers who can follow-up during the trial period during the trial period
• If you have severe acute kidney or heart disease or other chronic illness that may affect your test results in the last 6 months
• Have experience with finasteride or other 5a-Reductase inhibitors within 12 months before screening.
• If you have experience using plant remedies (eg saw palmetto) within 8 weeks before screening
• Use of glucocorticoids within 3 months prior to screening (inhaled glucocorticoids allowed; topical steroids are allowed if not used on scalp)
• Usage 6 months before screening :
? Minoxidil (oral or topical)
? Drugs with antiandrogenic properties (eg cyproterone acetate, spironolactone, ketoconazole, flutamide, and bicalutamide). Cimetidine can not be used during the trial period, but it has not been used for the last 6 months.
? Local estrogen, progesterone
? Tamoxifen
? Drugs that can cause hyperhidrosis to cause hyperactivity (eg cyclosporine, diazoxide, phenytoin psoralens)
? Anabolic steroids
? Lithium and phenothiazine
• Use of past cytotoxic agents
• Simultaneous or regular use of topical agents on scalp for 4 weeks before screening
• Have received surgical treatment for hair loss such as hair transplantation or scalp reduction
• You have used other products that have been called "hairballs" within the last 3 months.
• Have recently taken or are currently taking medications that may affect hair growth
• If you are suffering from alopecia due to causes other than male hair loss
• Others who are unable to communicate or who are unable to follow instructions
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hair density
- Secondary Outcome Measures
Name Time Method mean hair diameter;linear hair growth rate;ratio of the anagen hair;non-vellus hair count