Transfemoral Versus Transradial Approach in Transarterial Chemoembolization of Hepatocellular Carcinoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hepatocellular Carcinoma
- Sponsor
- Assiut University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- To compare transfemoral approach (TFA) and transradial approach (TRA) in patients undergoing hepatic chemoembolization
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
Transfemoral Versus Transradial Approach in Transarterial Chemoembolization of Hepatocellular Carcinoma
Detailed Description
To compare transfemoral approach (TFA) and transradial approach (TRA) in patients undergoing hepatic chemoembolization in terms of safety, feasibility, and procedural variables, including fluoroscopy time and patient preference.
Investigators
Ali Adel Abouelmagd Sewisy
M.B.B.CH at Radiology department of Assuit university
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Patients with Hepatocellular carcinoma of BCLC (Barcelona Clinic Liver Cancer) stage B
- •Also for BCLC stage A patients, in whom ablative therapy has technical limitations.
- •Downsizing tumor for resection or transplantation.
Exclusion Criteria
- •Factors related to liver cirrhosis:
- •Decompensated cirrhosis (Child-Pugh B and C, score \>8), including jaundice, clinical hepatic encephalopathy, and refractory ascites and/ or hepatorenal syndrome
- •Impaired portal-vein blood flow (portal-vein thrombus, hepatofugal blood flow)
- •Factors related to HCC:
- •Extensive tumor involving the entirety of both lobes of the liver
- •Malignant portal vein thrombosis
- •Extra-hepatic metastases
- •Impaired renal function:
- •Creatinine ≥2 mg/dl or creatinine clearance \<30 ml/min
- •Factors related to procedure (Radial artery access):
Outcomes
Primary Outcomes
To compare transfemoral approach (TFA) and transradial approach (TRA) in patients undergoing hepatic chemoembolization
Time Frame: Baseline
To compare transfemoral approach (TFA) and transradial approach (TRA) in patients undergoing hepatic chemoembolization in terms of safety, feasibility, and procedural variables, including fluoroscopy time and patient preference.