Are Corneal Epithelial Defects Related to Changes in Ocular Bacterial Flora in Patients With ANLDO

• Conditions: Acquired Nasolacrimal Duct Obstruction

• Registration Number: NCT02234700
• Lead Sponsor: Western Galilee Hospital-Nahariya

Brief Summary

Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.

Detailed Description

Any patient with nasolacrimal duct obstruction above the age of 18 Comparing changes in their bacterial ocular flora to healthy patients without obstruction and above 18 years of age

Study Timeline

• Study Start: 2014-08
• Study First Submitted: 2014-08-26
• Status Verified: 2014-09
• Study First Submitted QC: 2014-09-08
• Last Update Submitted: 2014-09-08
• Study First Posted: 2014-09-09
• Last Update Posted: 2014-09-09
• Primary Completion: 2015-02
• Study Completion: 2015-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 18 years of age or older, nasolacrimal duct obstruction

Exclusion Criteria

• younger then 18 years of age
• ocular infections
• patients after repair of lacrimal duct surgery
• systemic active diseases
• patients taking medication that are know to influence bacterial flora of the eye

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the change of ocular normal flora in patients with nasolacrimal duct obstruction as a comparison to general population.	6 month	as the literature suggests most of the ocular flora is composed of Staphylococcus and Haemophilus, any change in these composition will be considered abnormal.

Trial Locations

Locations (1)

Western Galileeh Hospital; 🇮🇱 Naharya, Israel