NCT02234700Unknown不适用
To Estimate Whether Corneal Epithelial Defects Occur in Patients With Acquired Nasolacrimal Duct Obstructions is Linked to Changes Occurring Within Ocular Bacterial Flora in These Patients, and What Are the Specific Changes in Their Flora.
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the change of ocular normal flora in patients with nasolacrimal duct obstruction as a comparison to general population.
研究概览
简要总结
Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.
详细描述
Any patient with nasolacrimal duct obstruction above the age of 18 Comparing changes in their bacterial ocular flora to healthy patients without obstruction and above 18 years of age
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age or older, nasolacrimal duct obstruction
排除标准
- •younger then 18 years of age
- •ocular infections
- •patients after repair of lacrimal duct surgery
- •systemic active diseases
- •patients taking medication that are know to influence bacterial flora of the eye
结局指标
主要结局
the change of ocular normal flora in patients with nasolacrimal duct obstruction as a comparison to general population.
时间窗: 6 month
as the literature suggests most of the ocular flora is composed of Staphylococcus and Haemophilus, any change in these composition will be considered abnormal.
次要结局
未报告次要终点
研究者
研究点 (1)
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