Weight-reduction Intervention in Asthmatic Children With Overweight/Obesity
Not Applicable
Completed
- Conditions
- AsthmaOverweightObesity
- Interventions
- Behavioral: Multifaceted intervention
- Registration Number
- NCT00998413
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
The purpose of this study is to determine the efficacy of a multifactorial intervention with weight reduction, behavioural therapy, and physical exercise on the severity and control of asthma in obese children.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 87
Inclusion Criteria
- Children aged 6-16 years
- BMI in the overweight/obesity range according to data of Cole et al.
- Asthma diagnosis
Exclusion Criteria
- Children with a normal weight according to data of Cole et al.
- Children without any provable asthmatic complaints
- Congenital malformations of the airways or other chronic lung diseases like cystic fibrosis (CF)
- Mental retardation or syndromes
- Heart disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Multifaceted intervention Multifaceted intervention Multifaceted intervention:physical exercise, nutrition, and behavioural intervention.
- Primary Outcome Measures
Name Time Method Forced Expiratory Volume in the first second (FEV1 %) predicted value 2 years
- Secondary Outcome Measures
Name Time Method Airway inflammation 2 years Symptom-free days, exacerbations 2 years Need for beta-2 agonists/anti-inflammatory medication 2 years Weight, height, body mass index (BMI) 2 years Levels of serum adipokines 2 years aerobic capacity 2 years VO2max measured with an maximal ergometry test
Trial Locations
- Locations (1)
Maastricht University Medical Centre
🇳🇱Maastricht, Limburg, Netherlands