Biological Rhythms and Vestibular System
Not Applicable
- Conditions
- Unspecified Disorder of Vestibular Function, Bilateral
- Interventions
- Behavioral: vestibular stimulation
- Registration Number
- NCT01839409
- Lead Sponsor
- University Hospital, Caen
- Brief Summary
The purpose of this study is to study the relationship between the vestibular system and chronobiology
- Detailed Description
The purpose of this study is to study the relationship between the vestibular system and chronobiology.
Two parts will be performed. In the first one patients with bilateral vestibular areflexia will be compared to control subjects.
In the second the effect of vestibular stimulation on circadian rhythms will be evaluated
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
- No treatment changing vigilance/wakefulness
- Moderate caffein uptake (2 to 3 cups a day)
- Moderate smoker (5 cigarettes a day)
- Regular sleeping habits
Exclusion Criteria
- Sleeping duration <6 hours or >9 hours
- Night workers
- Pregnancy
- Sleep or wakefulness disorders
- Progressive neurodegenerative disorders
- Progressive psychiatric disorders
- Thyroid disease
- Type 1 diabetes
- Not able to practice physical activity
- Drug or alcohol addiction during the last 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description vestibular stimulation vestibular stimulation Subjects submitted to vestibular stimulation in order to improve circadian rhythms
- Primary Outcome Measures
Name Time Method Measurements of vestibular reflexes (ocular and spinal) and circadian rhythms of biological functions. 3 years Gain of vestibular ocular reflex Amplitude of vestibular spinal reflex Amplitude and phase of temperature circardian rhythms
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Umr Ucbn/Inserm U1075 Comete
🇫🇷Caen CEDEX, Basse-Normandie, France