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Effects of body mass index (BMI) and smoking on the pharmacokinetics of fentanyl

Completed
Conditions
All patients using a stable dose of a fentanyl (Durogesic ®) patch (for at least 8 days).
Registration Number
NL-OMON28290
Lead Sponsor
Erasmus Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

•age > 18 years;

•stable use and dose of fentanyl patch (Durogesic ®) for at least 8 days, irrespective of the dose used;

Exclusion Criteria

•Using fentanyl as rescue medication (other opioids are allowed)

•Serious psychiatric illness, confusion of intellectual disability

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main study parameters/endpoints. Pharmacokinetics (clearance, AUC etc)<br>
Secondary Outcome Measures
NameTimeMethod
not applicable
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