High dose Coenzyme Q10 and vitamin E therapy in Friedreich's ataxia

Completed

• Conditions: Friedreich's ataxia; Nervous System Diseases

• Registration Number: ISRCTN87024790
• Lead Sponsor: Royal Free Hospital Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

1. Homozygous for the GAA expansion in the FRDA gene characteristic of the disease
2. Able and willing to attend the assessments over the trial period
3. Over 10 years of age at the start of the trial

Exclusion Criteria

1. Planned surgery during the trial period
2. An ICARS score greater than 80% of the maximum
3. Taking coenzyme Q10, vitamin E or other antioxidants
4. Planned pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified