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Metacognitive Training in the Older Adults With Depressive Symptoms (MCT-Silver)

Not Applicable
Recruiting
Conditions
Depressive Symptoms
Interventions
Behavioral: Metacognitive Training for Depression in Later Life (MCT-Silver)
Registration Number
NCT05640492
Lead Sponsor
University of Évora
Brief Summary

Depression is one of the most common mental disorders in older adults and a major cause of years lived with disability. Depression does not always respond to antidepressants, and non-pharmacological interventions are recommended by international guidelines. The Metacognitive Training for Depression in Later Life (MCT-Silver) is a creative and innovative group intervention that aims to reduce depressive symptoms by challenging the cognitive and metacognitive beliefs characteristic of this disorder, that intends to enable participants to recognize and correct their automatic and dysfunctional thinking patterns and behavior. It was developed by the partner institution's team, and has already demonstrated positive results. This project aims to extend the research study to Portugal, through cultural adaptation, pilot study, and a Randomized Controlled Trial (RCT). To this end, we defined the following aims: To plan and conduct a pilot study to assess the efficacy of the MCT-Silver in the Portuguese population; To conduct a multicenter randomized controlled trial (RCT).

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
120
Inclusion Criteria
  • Ability to give informed consent
  • Age: 60 years or older
  • Sufficient command of the Portuguese language
  • Willingness to participate in the intervention for a period of 4 to 8 weeks (participants who do not participate in the intervention will also be included in the analysis)
  • Adequate visual and hearing acuity for neuropsychological testing and participation in the group sessions
  • Values above 10 on the Hamilton Depression Scale
Exclusion Criteria
  • Active psychotic symptoms (i.e., hallucinations, delusions, or manias)
  • Acute suicidal ideation
  • Cognitive impairment
  • Dementia or other neurological disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
MCT GroupMetacognitive Training for Depression in Later Life (MCT-Silver)Older adults (more than 59 years old) with depressive symptoms
Primary Outcome Measures
NameTimeMethod
Hamilton Depression Rating Scale (HRSD-24)Follow-up (6 months after the intervention)

The 24-item version of the Hamilton Depression Rating Scale is an established clinician-

Secondary Outcome Measures
NameTimeMethod
Dysfunctional Attitudes Scale Form 18B (DAS-18B)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in dysfunctional attitudes as measured by change in the Dysfunctional Attitudes Scale Form 18B (DAS-18B) total score and subscale scores from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). Each item is endorsed on a 7-point scale (Range: 0-7) such that a total score of 126 is possible with higher scores indicating dysfunctional beliefs which are held more strongly. The total score is comprised of two subscales (perfectionism (Range 0-56); need for social approval (Range 0-21)), which are summed along with 7 other items to calculate the total scale score.

Beck-Depressions-Inventar II (BDI-II)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in self-assessed depression as measured by the Beck Depression Inventory (BDI) total score from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). The BDI is a 21-item self-report measure of depression symptoms. Total scores range from 0-63 with higher scores indicating more severe levels of depression.

Mini Mental State Examination (MMSE)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Developed by Folstein et al, 1975 to assess cognitive deficits.

Attitudes to Ageing Questionnaire (AAQ)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

The attitudes to ageing questionnaire (AAQ) \[12\] was developed to provide a standard way of measuring attitudes to ageing from the perspective of older people.

Ruminative Responses ScaleTotal Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in rumination as measured by the Ruminative Responses Scale total score from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). The scale is comprised of 10 items and scores range from 10-40 with higher scores indicating higher self-esteem.

World Health Organization Quality of Life-BREF - Item 1Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in global quality of life as measured by change on item 1 on the World Health Organization Quality of Life-BREF from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). Responses on the item range from 1 (very bad quality of life) to 5 (very good quality of life).

Patient Health Questionnaire 9 (PHQ-9)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

9-item scale developed to assess depressive symptoms and to evaluate the symptoms of depression.

Metacognitions Questionnaire (MCQ-30)Total Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in metacognitive beliefs as measured by change in the Metacognitions Questionnaire (MCQ-30) total score and subscale scores from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). The 30-item scale has a range of 30-120. The scale is comprised of five subscales (range for each = 6-24): (1) Positive Beliefs (PB) about worry (6 items); (2) Negative Beliefs (NB) about thoughts concerning uncontrollability and danger (6 items), and (3) beliefs about the need to control thoughts (Need for Control \[NFC\],6 items); (4) Cognitive Confidence (6 items) and Cognitive Self-Consciousness (6 items). Higher scores indicate more strongly held metacognitive beliefs.

ICF Core Set for DepressionTotal Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

was developed through the WHO International Classification of Functioning, Disability and Health (Cieza et al., 2004), and criteria are being developed to make the assessment more objective, through the modified e-Delphi technique.

Rosenberg Self-Esteem ScaleTotal Time Frame is 7 months. Outcome is assessed at three points: baseline; post-intervention and Follow-up (6 months after the intervention)]

Change in self-esteem as measured by change in the Rosenberg Self-Esteem scale total score from baseline to post-assessment (8 weeks) and baseline to follow-up (5 months). The scale is comprised of 10 items and scores range from 10-40 with higher scores indicating higher self-esteem.

Trial Locations

Locations (1)

Lara Manuela Guedes de Pinho

🇵🇹

Évora, Portugal

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